2020 · In vitro cell research
Liposome co-delivery of Hispolon and Doxorubicin
Al Saqr et al. · AAPS PharmSciTech 21, 304
DOI: 10.1208/s12249-020-01846-2
Original publication & bibliographic recordRead the study summary06 / REFERENCES & SOURCES
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We introduce research developments through original papers and provide references for our company history, R&D programs and public announcements. Literature review date: October 2, 2026.
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Follow the summary back to the source.
We retain study identifiers, links to original papers and corporate references to help you understand the background of our research, programs and milestones. Please consider the dates and research stages alongside the content.
Publications & Trial Registry
29 entries: including 1 dissertation, 1 experimental registration and 1 study on P. igniarius related taxa. R20 only checks the bibliography, R25 simultaneously checks the 2019 author institution corrections. Data verification date 2026-10-02.
Download document classification CSVThe following are external academic studies and do not represent execution by eGreen or use of eGreen raw materials.
2023 · In vitro cell research
DHME derivatives and the SRC/STAT3/BCL-2 pathway
Hsieh et al. · Biomedicines 11(9), 2530
DOI: 10.3390/biomedicines11092530
Original publication & bibliographic recordRead the study summary2025 · Human retrospective study
Observational study of postoperative patients with pancreatic cancer
Kim et al. · Integrative Cancer Therapies
DOI: 10.1177/15347354251353499
Original publication & bibliographic recordRead the study summary2022 · Human randomized pilot trial
Immune function pilot trial: observation indicators and research design
Ku & Kang · Medicine 101(40), e30829
DOI: 10.1097/MD.0000000000030829
Original publication & bibliographic recordRead the study summary2014 · In vitro cell research
Study on Hispolon and apoptosis of nasopharyngeal carcinoma cells
Phytomedicine 21, 1746–1752
Hispolon from Phellinus linteus possesses mediate caspases activation and induces human nasopharyngeal carcinomas cells apoptosis through ERK1/2, JNK1/2 and p38 MAPK pathway.
DOI: 10.1016/j.phymed.2014.07.013
Original publication & bibliographic recordRead the study summary2021 · Species Identification Research
Clarifying the species identity of Sanghuang using ITS barcodes
IMA Fungus · PMID 33853671
Addressing widespread misidentifications of traditional medicinal mushrooms in Sanghuangporus (Basidiomycota) through ITS barcoding and designation of reference sequences.
DOI: 10.1186/s43008-021-00059-x
Original publication & bibliographic recordRead the study summary2022 · Human randomized controlled trial
98 human immune function test: NK cell activity
Ku, Kang & Lee · Medicine 101(34), e30226
DOI: 10.1097/MD.0000000000030226
Original publication & bibliographic recordRead the study summary2025 · Culture process and cell research
How do culture conditions affect Hispolon output?
Chueaphromsri et al. · Biotechnology Letters 47, 29
DOI: 10.1007/s10529-025-03561-z
Original publication & bibliographic recordRead the study summary2022 · Polysaccharide structure and cell research
S. vaninii polysaccharide fractionation and lung cancer cells
Wan et al. · Carbohydrate Polymers 276, 118798
DOI: 10.1016/j.carbpol.2021.118798
Original publication & bibliographic recordRead the study summary2024 · Fermentation and in vitro activity research
Optimization of liquid fermentation and strain differences
Gao et al. · Foods 13(8), 1190
DOI: 10.3390/foods13081190
Original publication & bibliographic recordRead the study summary2023 · Animal tumor research
S. baumii aqueous extract, autophagy and tumor model
Wu et al. · Food & Function 14, 2374–2384
DOI: 10.1039/D2FO02887E
Original publication & bibliographic recordRead the study summary2023 · Cell and Animal Research
Sanghuang ethanol extract and STAT3 clues in lung cancer
Wang et al. · Nutrition Research and Practice 17(6), 1070–1083
DOI: 10.4162/nrp.2023.17.6.1070
Original publication & bibliographic recordRead the study summary2025 · Research on animal intestinal injury
Protective mechanism in 5-FU-induced intestinal injury
Lin et al. · International Journal of Molecular Sciences 26(7), 3444
DOI: 10.3390/ijms26073444
Original publication & bibliographic recordRead the study summary2025 · Component Analysis and In Vitro Testing
UPLC-MS metabolite profiling of Sanghuang
Wang et al. · PeerJ 13, e18758
DOI: 10.7717/peerj.18758
Original publication & bibliographic recordRead the study summary2019 · Human retrospective study
Pancreatic cancer: study on completion of postoperative adjuvant therapy
Lee et al. · Integrative Cancer Therapies 18
Potential Impact of Phellinus linteus on Adherence to Adjuvant Treatment After Curative Resection of Pancreatic Ductal Adenocarcinoma: Outcomes of a Propensity Score-Matched Analysis.
DOI: 10.1177/1534735418816825
Original publication & bibliographic recordRead the study summary2008 · Human pre–post observational study
Atopic dermatitis in children: 12-week symptom tracking
Hong et al. · The Korea Journal of Herbology 23(1), 103–108
Original publication & bibliographic recordRead the study summary2010 · Human pre–post observational study
Atopic dermatitis: topical formulations and skin barrier
Jeong et al. · J Korean Oriental Medical Ophthalmology & Otolaryngology & Dermatology 23(3), 154–164
Original publication & bibliographic recordRead the study summary2004 · Single case report
Prostate cancer: Evidence positioning in early case literature
Shibata et al. · Urologia Internationalis 73(2), 188–190
Dramatic remission of hormone refractory prostate cancer achieved with extract of the mushroom, Phellinus linteus.
DOI: 10.1159/000079704
Original publication & bibliographic recordRead the study summary2006 · Single case report
Hepatocellular carcinoma: case clues to spontaneous regression
Kojima et al. · Radiation Medicine 24
A case of spontaneous regression of hepatocellular carcinoma with multiple lung metastases.
DOI: 10.1007/bf02493281
Original publication & bibliographic recordRead the study summary2011 · Safety case report · bibliographic record
Report of exacerbation of pemphigus after ingestion of PL
Jin, Hong & Chung · JEADV 25(4), 492–493
Exacerbation of pemphigus following Phellinus linteus ingestion.
DOI: 10.1111/j.1468-3083.2010.03746.x
Original publication & bibliographic recordRead the study summary2021 · Taiwan·Animal Research
Sanghuang mycelium and drug-induced liver injury
Jiang et al. · Antioxidants 10(6), 897
Sanghuangporus sanghuang Mycelium Prevents Paracetamol-Induced Hepatotoxicity through Regulating the MAPK/NF-κB, Keap1/Nrf2/HO-1, TLR4/PI3K/Akt, and CaMKKβ/LKB1/AMPK Pathways and Suppressing Oxidative Stress and Inflammation.
DOI: 10.3390/antiox10060897
Original publication & bibliographic recordRead the study summary2022 · Animal Metabolism Research
Type 2 diabetic mice: polysaccharides, blood glucose and bacteria
Huang et al. · Frontiers in Nutrition 9, 1013466
Sanghuangporus vaninii fruit body polysaccharide alleviates hyperglycemia and hyperlipidemia via modulating intestinal microflora in type 2 diabetic mice.
DOI: 10.3389/fnut.2022.1013466
Original publication & bibliographic recordRead the study summary2024 · Research on microbiota and animal mechanism
Mechanism of enteritis: bacteria, 5-HIAA and AhR
Zhong et al. · iMeta 3, e180
The gut microbiota-aromatic hydrocarbon receptor (AhR) axis mediates the anticolitic effect of polyphenol-rich extracts from Sanghuangporus.
DOI: 10.1002/imt2.180
Original publication & bibliographic recordRead the study summary2023 · Taiwan’s participation in cell research
Triple-negative breast cancer: MHME and SRC/STAT3
Liao et al. · Biomedicines 11(10), 2742
Methoxyhispolon Methyl Ether, a Hispolon Analog, Thwarts the SRC/STAT3/BCL-2 Axis to Provoke Human Triple-Negative Breast Cancer Cell Apoptosis In Vitro.
DOI: 10.3390/biomedicines11102742
Original publication & bibliographic recordRead the study summary2017 · Taiwan·Cell Research
Hispidin and glycation stress in neural cells
Song et al. · Oxidative Medicine and Cellular Longevity 2017, 4824371
Protective Effects and Possible Mechanisms of Ergothioneine and Hispidin against Methylglyoxal-Induced Injuries in Rat Pheochromocytoma Cells.
DOI: 10.1155/2017/4824371
Original publication & bibliographic recordRead the study summary2024 · Taiwan Master’s Thesis・Cell Model
Sanghuangporus sanghuang and Sanghuangporus vitexicola: inflammation and glucose uptake
Lin · Master’s Thesis, Department of Plant Pathology, National Chung Hsing University
Original publication & bibliographic recordRead the study summary2026 · Taiwan trial registry · no results posted
National Sports University: Sanghuang and fatigue resistance test
National Taiwan Sport University · ClinicalTrials.gov NCT06902662
Original publication & bibliographic recordRead the study summary2017 · Cell and Animal Tumor Research
KRAS mutated colorectal cancer: cetuximab sensitivity
Park et al. · International Journal of Molecular Sciences 18(8), 1746
Phellinus linteus Grown on Germinated Brown Rice Increases Cetuximab Sensitivity of KRAS-Mutated Colon Cancer.
DOI: 10.3390/ijms18081746
Original publication & bibliographic recordRead the study summary2026 · Related species · human randomized trial
P. igniarius: study on immunity after chemotherapy for colorectal cancer
Zhang et al. · Journal of Traditional and Complementary Medicine
A prospective clinical study on the effectiveness of Phellinus igniarius decoction in treating immune dysfunction in colorectal cancer patients following chemfotherapy.
DOI: 10.1016/j.jtcme.2026.05.002
Original publication & bibliographic recordRead the study summaryCompany & public records
Corporate overview · 2026
eGreen Biotek 2026 Introduction
History: Page 4; Cultivation, Quality and Laboratory: Pages 5–7; International Research Context: Page 9; Company Pilot Research: Pages 22–28; R&D Plan: Page 30; Contact Information: Page 49.
We distinguish our own R&D progress from external journal research so you can understand the background, research stage and scope of each finding.
Internal strategy information · 2026
Annual shareholders’ meeting presentation, ROC year 115 (2026), version 0625
Refer to the AI tool introduction guidance on page 7, and the internal control, governance and capital market preparation directions on pages 10 and 30; internal financial and business conditions or unimplemented plans are not regarded as public results.
Governance and capital-market information is disclosed within the approved scope, with subsequent developments communicated through formal announcements.
Cabinet Buying Center Announcement · 2017
Announcement of eGreen Biotek Corp. registration on the Go Incubation Board
Document number: Zhengaixinzi No. 10600256991; stock code 7525, company abbreviation eGreen Biotek. This announcement is for historical milestones and not for inferring real-time market status.
Original announcement of cabinet buying centerPublic media reports · 2025.05.15
Cooperation between eGreen and AMP Laboratory and planning of mushroom technology center
Source: Daqian Radio/Yahoo News. Used to confirm the then disclosed descriptions of raw material supply, OEM and North American market cooperation.
The description of the factory area and regulations in the article is the current plan and does not mean that this website has verified the completion of the facility, GMP certification or FDA approval.
Read the original reportCEO education & career
Juiche Hsieh: biography and career information
Juiche Hsieh served as eGreen Biotek's CTO from 2009 to 2016 and has served as CEO since 2016. His education and international roles are documented in the eGreen Biotek Juiche Hsieh biography and professional profile.
LinkedIn profileTaipei Exchange official framework
GISA purpose and framework
Taipei Exchange describes GISA's business-advisory and equity-fundraising role and explicitly states that the platform does not provide trading. This source explains the distinction between GISA and other market boards.
About GISAGovernment plans and industry-university information
We provide dates, research directions and references for past programs. Dates prioritize public government approvals, followed by earlier project records; differences between versions are noted for each project. Application documents containing personal contact or business information are summarized only as needed.
Company plan information · 2022
Hsinchu City local SBIR initial review presentation, ROC year 111 (2022)
File: 111eGreen Biotek-Initial Review Report PPT220804_v2.pptx. Page 1 is the name, period and management organization of the project; Page 3 is the previous years’ plans; the rest of the research content is interpreted according to the initial plan.
Company plan information · 2020
Application Brief for Instant Counseling for Small and Medium-sized Manufacturing Industries
File: 1091104 Small and medium-sized manufacturing industry instant tutoring application brief R2.pptx. Page 6 lists the 103–108 government plans and food industry-university cooperation, and subsequent pages describe instant powder development and expected benefits. The application and calendar do not replace the approval letter or case closing information.
Application and review information · 2023
Technical-assistance documents on bioprocessed cereal-flour materials, ROC year 112 (2023)
In 2023, we applied for technical assistance for bioprocessed cereal-flour materials under the then Industrial Development Bureau of the Ministry of Economic Affairs, with the Food Industry Research and Development Institute as the technical-assistance body. References include application version 1120322-final and the review presentation dated March 31, 2023. Quantified improvements are application targets, not measured outcomes.
Government’s public subsidy records
Approval record of Sanghuang machining process optimization plan
Our Sanghuang process-optimization project was approved on November 6 of ROC year 103, as recorded in the Industrial Development Bureau's public quarterly subsidy report. We use this approval date, which differs from the year shown in the 2026 retrospective version.
The Ministry of Economic Affairs discloses subsidy recordsGovernment’s public subsidy records · 2016
Approval record of LED cultivation fruiting body mass production plan
Our LED-cultivated fruiting-body scale-up project was approved on July 4 of ROC year 105, as recorded on page 2 of the Industrial Development Bureau's third-quarter report for that year. Subsidy approval, technical outcomes and project completion are verified separately.
The Ministry of Economic Affairs discloses subsidy recordsR&D experiment records · 2021
Just-in-time tutoring program pilot briefing
File: real-time tutoring plan.pptx. Save records of cell tests, immune-related indicators and component analysis in 2021; they are only used to confirm existing test data and will not be regarded as human efficacy or government case closure results.
Original drawings and authorization of literature experiments
The research page contains six sets of figures (eight original figure files) of R2, R10, and R13, obtained through the Europe PMC open access API, and presented under the CC BY 4.0 license indicated in each paper. The complete original image is retained and only scaled by the web page; the author, image number, source and authorization are listed below the image. The Chinese introduction is compiled by this website and does not constitute an endorsement of eGreen by the original author or the journal.
Go to the original image of the experiment · Download chart source and authorization record · CC BY 4.0 License Terms